Traditional methods for measuring allergen skin prick or intradermal testing is tedious, error prone and does not integrate well with electronic medical records. There is poor standardization across hospitals and clinics around the world. As seen in images A-C the wheal and flare response can be difficult to measure with the naked eye. This may lead to errors. In the case of brittle asthmatics, drug allergy or food allergy related anaphylaxis, errors in interpretation of the results may have disastrous consequences.

Image B and C shows skin prick testing on two African American patients. In individuals with darker skin tones, traditional measurement are often very difficult to determine. In some cases the erythematous region can be nearly undetectable to the human eye.